<?xml version="1.0" encoding="utf-8"?>
<XML>
	<ISCJOURNAL>
		<YEAR>2023</YEAR>
		<VOL>5</VOL>
		<NO>16</NO>
		<MOSALSAL>16</MOSALSAL>
		<PAGE_NO>10</PAGE_NO>
		<ARTICLES>
			<DOI>10.61186/jcc.5.3.4</DOI>
			<ARTICLE>
				<TitleF/>
				<TitleE>Bredigite-containing materials for regenerative medicine applications: A 
					rapid review</TitleE>
				<TitleLang_ID>1</TitleLang_ID>
				<ABSTRACTS>
					<ABSTRACT>
						<Language_ID>1</Language_ID>
						<CONTENT>Bredigite (BR; Ca7MgSi4O16) is known as one of the most popular calcium-silicate bioceramics. It has an orthorhombic
							structure containing calcium silicate magnesium compound, and releases Si ions, thereby inducing 
							precursor cell differentiation and cell growth. This suggests that Br may serve as a promising material for existing 
							orthopedic and dental implants. A new insight into the Br composites structure/activity/application tradeoff is the 
							primary objective of the current review, which helps researchers overcome the existing challenges and recognize 
							the bottlenecks that arose from this intersection. In this rapid review, the state-of-the-art advances in Br-containing 
							composites in terms of preparation techniques and modifying methods for enhancing their functional properties, 
							especially in the field of dental implants are surveyed and discussed</CONTENT>
					</ABSTRACT>
				</ABSTRACTS>
				<PAGES>
					<PAGE>
						<FPAGE>190</FPAGE>
						<TPAGE>199</TPAGE>
					</PAGE>
				</PAGES>

				<AUTHORS>
					<AUTHOR>
						<NameE>Amirhosein</NameE>
						<MidNameE/>
						<FamilyE>Shahbaz</FamilyE>
						<Organizations>
							<Organization>Department of Materials Engineering, Karaj Branch, Islamic Azad University</Organization>
						</Organizations>						
						<Countries>
							<Country>Iran</Country>
						</Countries>
						<EMAILS>
							<Email>amirhosein.shahbaz@gmail.com</Email>
						</EMAILS>
					</AUTHOR>
					<AUTHOR>
						<NameE> Neda</NameE>
						<MidNameE/>
						<FamilyE>Tajbakhsh</FamilyE>
						<Organizations>
							<Organization>Department of Prosthodontics, School of Dentistry, Islamic Azad University, Tehran Dental Branch</Organization>
						</Organizations>						
						<Countries>
							<Country>Iran</Country>
						</Countries>
						<EMAILS>
							<Email>info@jourcc.com</Email>
						</EMAILS>											
					</AUTHOR>
					<AUTHOR>
						<NameE>Aidin</NameE>
						<MidNameE/>
						<FamilyE>Doroudi</FamilyE>
						<Organizations>
							<Organization>Polymer and Color Engineering Department, Amirkabir University of Technology</Organization>
						</Organizations>						
						<Countries>
							<Country>Iran</Country>
						</Countries>
						<EMAILS>
							<Email>info@jourcc.com</Email>
						</EMAILS>											
					</AUTHOR>
					<AUTHOR>
						<NameE>Fatemeh</NameE>
						<MidNameE/>
						<FamilyE>Bakhshi</FamilyE>
						<Organizations>
							<Organization>Polymer and Color Engineering Department, Amirkabir University of Technology</Organization>
						</Organizations>						
						<Countries>
							<Country>Iran</Country>
						</Countries>
						<EMAILS>
							<Email>info@jourcc.com</Email>
						</EMAILS>											
					</AUTHOR><AUTHOR>
						<NameE>Samira</NameE>
						<MidNameE/>
						<FamilyE>Ranjbar</FamilyE>
						<Organizations>
							<Organization>Department of Materials and Metallurgical Engineering, Amirkabir University of Technology</Organization>
						</Organizations>						
						<Countries>
							<Country>Iran</Country>
						</Countries>
						<EMAILS>
							<Email>info@jourcc.com</Email>
						</EMAILS>											
					</AUTHOR>
				</AUTHORS>
				<KEYWORDS>
					<KEYWORD>
						<KeyText>Bredigite</KeyText>
					</KEYWORD>
					<KEYWORD>
						<KeyText>Regenerative Medicine</KeyText>
					</KEYWORD>
					<KEYWORD>
						<KeyText>Dental Implants</KeyText>
					</KEYWORD>
					<KEYWORD>
						<KeyText>Composites</KeyText>				
					</KEYWORD>
				</KEYWORDS>
				<PDFFileName>Article4.pdf</PDFFileName>
				<REFRENCES>
					<REFRENCE>
						<REF>[1] S. Amirfarhangi, A. Vakili, L. Radfar, N. Tajbakhsh, Golden proportion and 
							facial esthetic, the harmony and surgical considerations: A review, World Journal 
							of Biology, Pharmacy and Health Sciences 11(01) (2022) 018–021.##[2] N. Tajbakhsh, F. Delpisheh, N. Ghadimi, S. Ansari, Smile management: White 
							esthetic, pink esthetic and facial attractiveness, a review of literature, Open Access 
							Research Journal of Biology and Pharmacy 05(02) (2022) 046–050.##[3] A.B. Berezow, R.P. Darveau, Microbial shift and periodontitis, Periodontol 
							2000 55(1) (2011) 36-47.##[4] A. Murua, E. Herran, G. Orive, M. Igartua, F.J. Blanco, J.L. Pedraz, R.M. 
							Hernández, Design of a composite drug delivery system to prolong functionality of cell-based scaffolds, International Journal of Pharmaceutics 407(1) (2011) 
							142-150.##[5] Y. Zhou, C. Wu, X. Zhang, P. Han, Y. Xiao, The ionic products from bredigite 
							bioceramics induced cementogenic differentiation of periodontal ligament cells via 
							activation of the Wnt/β-catenin signalling pathway, Journal of Materials Chemistry 
							B 1(27) (2013) 3380-3389.##[6] Y. Tamaki, T. Nakahara, H. Ishikawa, S. Sato, In vitro analysis of mesenchymal 
							stem cells derived from human teeth and bone marrow, Odontology 101(2) (2013) 
							121-132.##[7] L. Liu, J. Ling, X. Wei, L. Wu, Y. Xiao, Stem Cell Regulatory Gene Expression 
							in Human Adult Dental Pulp and Periodontal Ligament Cells Undergoing Odontogenic/Osteogenic Differentiation, Journal of Endodontics 35(10) (2009) 1368-
							1376.##[8] J. Nuñez, S. Sanz-Blasco, F. Vignoletti, F. Muñoz, H. Arzate, C. Villalobos, L. 
							Nuñez, R.G. Caffesse, M. Sanz, Periodontal regeneration following implantation 
							of cementum and periodontal ligament-derived cells, Journal of Periodontal Research 47(1) (2012) 33-44.
							##[9] C. Wu, Y. Zhou, C. Lin, J. Chang, Y. Xiao, Strontium-containing mesoporous 
							bioactive glass scaffolds with improved osteogenic/cementogenic differentiation 
							of periodontal ligament cells for periodontal tissue engineering, Acta Biomaterialia 
							8(10) (2012) 3805-3815.##[10] L.L. Hench, J.M. Polak, Third-Generation Biomedical Materials, Science 
							295(5557) (2002) 1014-1017.##[11] K. Ji, Y. Liu, W. Lu, F. Yang, J. Yu, X. Wang, Q. Ma, Z. Yang, L. Wen, K. 
							Xuan, Periodontal tissue engineering with stem cells from the periodontal ligament 
							of human retained deciduous teeth, Journal of Periodontal Research 48(1) (2013) 
							105-116.##[12] C. Wu, J. Chang, W. Zhai, S. Ni, A novel bioactive porous bredigite (Ca7
							MgSi4O16) scaffold with biomimetic apatite layer for bone tissue engineering, Journal 
							of Materials Science: Materials in Medicine 18(5) (2007) 857-864.##[13] K. Kurashina, H. Kurita, Q. Wu, A. Ohtsuka, H. Kobayashi, Ectopic osteogenesis with biphasic ceramics of hydroxyapatite and tricalcium phosphate in rabbits, 
							Biomaterials 23(2) (2002) 407-412.##[14] M. Saito, H. Shimizu, M. Beppu, M. Takagi, The role of β-tricalcium phosphate in vascularized periosteum, Journal of Orthopaedic Science 5(3) (2000) 275-
							282.##[15] K. Ohura, M. Bohner, P. Hardouin, J. Lemaître, G. Pasquier, B. Flautre, Resorption of, and bone formation from, new β-tricalcium phosphate-monocalcium 
							phosphate cements: An in vivo study, Journal of Biomedical Materials Research 
							30(2) (1996) 193-200.##[16] K. Ohsawa, M. Neo, H. Matsuoka, H. Akiyama, H. Ito, H. Kohno, T. Nakamura, The expression of bone matrix protein mRNAs around β-TCP particles implanted into bone, Journal of Biomedical Materials Research 52(3) (2000) 460-466.
							##[17] X. Zhang, Y. Li, X. Dong, H. Wang, B. Chen, R. Li, Y. Qin, O. Ivasishin, 
							3D-printed bioactive ceramic scaffolds with MoSe2 nanocrystals as photothermal 
							agents for bone tumor therapy, RSC Advances 12(47) (2022) 30588-30597.##[18] C. Wu, J. Chang, Degradation, bioactivity, and cytocompatibility of diopside, 
							akermanite, and bredigite ceramics, Journal of Biomedical Materials Research Part 
							B: Applied Biomaterials 83B(1) (2007) 153-160.##[19] V. Kahlenberg, I. Galuskina, B. Krüger, A. Pauluhn, E. Galuskin, Structural 
							investigations on bredigite from the Hatrurim Complex, Mineralogy and Petrology 
							113(2) (2019) 261-272.##[20] G. Kaur, V. Kumar, F. Baino, J.C. Mauro, G. Pickrell, I. Evans, O. Bretcanu, 
							Mechanical properties of bioactive glasses, ceramics, glass-ceramics and composites: State-of-the-art review and future challenges, Materials Science and Engineering: C 104 (2019) 109895.
							##[21] A. Hamidi, K. Parham, U. Atikol, A.H. Shahbaz, A parametric performance 
							analysis of single and multi-effect distillation systems integrated with open-cycle 
							absorption heat transformers, Desalination 371 (2015) 37-45.##[22] M. Paidar, S. Ghavamian, O.O. Ojo, A. Khorram, A. Shahbaz, Modified friction stir clinching of dissimilar AA2024-T3 to AA7075-T6: Effect of tool rotational speed and penetration depth, Journal of Manufacturing Processes 47 (2019) 
							157-171.##[23] A. Shahbaz, M. Abbasi, H. Sabet, Effect of microstructure on mechanical, 
							electrochemical, and biological properties of Ti/HA surface composites fabricated 
							by FSP method, Materials Today Communications 37 (2023) 107305.##[24] A.H. Shahbaz, M. Esmaeilian, R. NasrAzadani, K. Gavanji, Effect of MgF2
							addition on the mechanical properties of hydroxyapatite synthesized via powder 
							metallurgy, Journal of Composites and Compounds 1(1) (2019) 16-21.##[25] C. Wu, J. Chang, Synthesis and In vitro Bioactivity of Bredigite Powders, 
							Journal of Biomaterials Applications 21(3) (2007) 251-263.##[26] C. Wu, J. Chang, J. Wang, S. Ni, W. Zhai, Preparation and characteristics of 
							a calcium magnesium silicate (bredigite) bioactive ceramic, Biomaterials 26(16) 
							(2005) 2925-2931.##[27] M. Kheradmandfard, S.F. Kashani-Bozorg, M.R. Barati, S. Sarfarazijami, A 
							novel strategy for fast and facile synthesis of bioactive bredigite nanoparticles using microwave-assisted method, Journal of Materials Research and Technology 25 
							(2023) 1735-1747.##[28] X. Bao, M. He, Z. Zhang, X. Liu, Crystal Structure and Some Thermodynamic 
							Properties of Ca7MgSi4O16-Bredigite, Crystals 11(1) (2021) 14.##[29] D. Yi, C. Wu, B. Ma, H. Ji, X. Zheng, J. Chang, Bioactive bredigite coating 
							with improved bonding strength, rapid apatite mineralization and excellent cytocompatibility, Journal of Biomaterials Applications 28(9) (2014) 1343-1353.
							##[30] S.N. Dezfuli, Z. Huan, A. Mol, S. Leeflang, J. Chang, J. Zhou, Advanced bredigite-containing magnesium-matrix composites for biodegradable bone implant 
							applications, Materials Science and Engineering: C 79 (2017) 647-660.##[31] P.B. Moore, T. Araki, The crystal structute of bredigite and the genealogy of 
							some alkaline earth orthosilicates, American Mineralogist 61(1-2) (1976) 74-87.##[32] M.P. Saradhi, U.V. Varadaraju, Photoluminescence Studies on Eu2+-Activated 
							Li2 SrSiO4 a Potential Orange-Yellow Phosphor for Solid-State Lighting, Chemistry of Materials 18(22) (2006) 5267-5272.
							##[33] J.K. Park, K.J. Choi, C.H. Kim, H.D. Park, S.Y. Choi, Optical Properties of 
							Eu2+ -Activated Sr2SiO4 Phosphor for Light-Emitting Diodes, Electrochemical and Solid-State Letters 7(5) (2004) H15.##[34] K.H. Lee, S. Choi, H.-K. Jung, W.B. Im, Bredigite-structure Ca14Mg2
							[-SiO4]8:Eu2+,Mn2+: A tunable green–red-emitting phosphor with efficient energyransfer for solid-state lighting, Acta Materialia 60(16) (2012) 5783-5790.
							##[35] K.H. Lee, S.H. Park, H.S. Yoon, Y.-I. Kim, H.G. Jang, W.B. Im, Bredigite-structure orthosilicate phosphor as a green component for white LED: the structural and optical properties, Optics Express 20(6) (2012) 6248-6257.
							##[36] K.H. Lee, W.B. Im, Efficiency Enhancement of Bredigite-Structure Ca14Mg2 [-SiO4 ]8
							:Eu2+ Phosphor via Partial Nitridation for Solid-State Lighting Applications, 
							Journal of the American Ceramic Society 96(2) (2013) 503-508. ##[37] S.J. Kim, H.S. Jang, S. Unithrattil, Y.H. Kim, W.B. Im, Enhanced Optical 
							Properties of Bredigite-Structure Ca13.7Eu0.3Mg2 [SiO4 ]8 Phosphor: Effective Eu Reduction by La Co-Doping, Journal of the American Ceramic Society 99(2) (2016) 
							557-563.##[38] M. Kouhi, V. Jayarama Reddy, M. Fathi, M. Shamanian, A. Valipouri, S. Ramakrishna, Poly (3-hydroxybutyrate-co-3-hydroxyvalerate)/fibrinogen/bredigite 
							nanofibrous membranes and their integration with osteoblasts for guided bone regeneration, Journal of Biomedical Materials Research Part A 107(6) (2019) 1154-
							1165.##[39] W.A. Jiranek, A.D. Hanssen, A.S. Greenwald, Current concepts review: Antibiotic-loaded bone cement for infection prophylaxis in total joint replacement, 
							Journal of Bone and Joint Surgery 88(11) (2006) 2487-2500.##[40] M.E. Hake, H. Young, D.J. Hak, P.F. Stahel, E.M. Hammerberg, C. Mauffrey, 
							Local antibiotic therapy strategies in orthopaedic trauma: Practical tips and tricks 
							and review of the literature, Injury 46(8) (2015) 1447-1456.##[41] A. Bolandparvaz Jahromi, E. Salahinejad, Competition of carrier bioresorption and drug release kinetics of vancomycin-loaded silicate macroporous microspheres to determine cell biocompatibility, Ceramics International 46(16, Part A) 
							(2020) 26156-26159.##[42] M. Diba, O.-M. Goudouri, F. Tapia, A.R. Boccaccini, Magnesium-containing bioactive polycrystalline silicate-based ceramics and glass-ceramics for biomedical applications, Current Opinion in Solid State and Materials Science 18(3) 
							(2014) 147-167.##[43] M. Diba, F. Tapia, A.R. Boccaccini, L.A. Strobel, Magnesium-Containing 
							Bioactive Glasses for Biomedical Applications, International Journal of Applied 
							Glass Science 3(3) (2012) 221-253.##[44] C. Wu, H. Zreiqat, Porous bioactive diopside (CaMgSi2
							O6) ceramic microspheres for drug delivery, Acta Biomaterialia 6(3) (2010) 820-829.##[45] N. Zirak, A. Bolandparvaz Jahromi, E. Salahinejad, Vancomycin release kinetics from Mg–Ca silicate porous microspheres developed for controlled drug 
							delivery, Ceramics International 46(1) (2020) 508-512.##[46] S.-W. Choi, Y. Zhang, Y.-C. Yeh, A. Lake Wooten, Y. Xia, Biodegradable porous beads and their potential applications in regenerative medicine, Journal of 
							Materials Chemistry 22(23) (2012) 11442-11451.##[47] N. Zirak, A.M. Maadani, E. Salahinejad, N. Abbasnezhad, M. Shirinbayan, 
							Fabrication, drug delivery kinetics and cell viability assay of PLGA-coated vancomycin-loaded silicate porous microspheres, Ceramics International 48(1) (2022) 
							48-54.##[48] A. Jadidi, F. Davoodian, E. Salahinejad, Effect of poly lactic-co-glycolic acid 
							encapsulation on drug delivery kinetics from vancomycin-impregnated Ca-Mg silicate scaffolds, Progress in Organic Coatings 149 (2020) 105970.
							##[49] A. Jadidi, E. Salahinejad, E. Sharifi, L. Tayebi, Drug-delivery Ca-Mg silicate scaffolds encapsulated in PLGA, International Journal of Pharmaceutics 589 
							(2020) 119855.##[50] T. Sopcak, L. Medvecky, P. Jevinova, M. Giretova, A. Mahun, L. Kobera, R. 
							Stulajterova, F. Kromka, V. Girman, M. Balaz, Physico-chemical, mechanical and 
							antibacterial properties of the boron modified biphasic larnite/bredigite cements 
							for potential use in dentistry, Ceramics International 49(4) (2023) 6531-6544.##[51] T. Sopcak, I. Shepa, T. Csanádi, L. Medvecky, M. Giretova, V. Kucharova, R. 
							Sedlak, K. Balazsi, R. Stulajterova, M. Streckova, Influence of boron addition on 
							the phase transformation, microstructure, mechanical and in-vitro cellular properties of bredigite-type coatings deposited by a spin coating technique, Materials 
							Chemistry and Physics 283 (2022) 126049. ##[52] L. Chen, L. Liu, C. Wu, R. Yang, J. Chang, X. Wei, The extracts of bredigite 
							bioceramics enhanced the pluripotency of human dental pulp cells, Journal of Biomedical Materials Research Part A 105(12) (2017) 3465-3474.
							##[53] P. Srinath, P. Abdul Azeem, K. Venugopal Reddy, Review on calcium silicate-based bioceramics in bone tissue engineering, International Journal of Applied Ceramic Technology 17(5) (2020) 2450-2464.
							##[54] X.-H. Huang, J. Chang, Preparation of nanocrystalline bredigite powders with 
							apatite-forming ability by a simple combustion method, Materials Research Bulletin 43(6) (2008) 1615-1620. 
							##[55] M. Rahmati, M. Fathi, M. Ahmadian, Preparation and structural characterization of bioactive bredigite (Ca7
							MgSi4 O16) nanopowder, Journal of Alloys and Compounds 732 (2018) 9-15.##[56] A. Khandan, N. Ozada, Bredigite-Magnetite (Ca7
							MgSi4O16-Fe3O4) nanoparticles: A study on their magnetic properties, Journal of Alloys and Compounds 726 
							(2017) 729-736.##[57] S. Sahmani, A. Khandan, S. Saber-Samandari, M.M. Aghdam, Nonlinear 
							bending and instability analysis of bioceramics composed with magnetite nanoparticles: Fabrication, characterization, and simulation, Ceramics International 44(8) 
							(2018) 9540-9549.##[58] F. Tavangarian, R. Emadi, Mechanism of nanostructure bredigite formation 
							by mechanical activation with thermal treatment, Materials Letters 65(15) (2011) 
							2354-2356.##[59] D. He, C. Zhuang, C. Chen, S. Xu, X. Yang, C. Yao, J. Ye, C. Gao, Z. Gou, Rational Design and Fabrication of Porous Calcium–Magnesium Silicate Constructs 
							That Enhance Angiogenesis and Improve Orbital Implantation, ACS Biomaterials 
							Science  Engineering 2(9) (2016) 1519-1527.##[60] Y. Shen, Z. Wang, J. Wang, Y. Zhou, H. Chen, C. Wu, M. Haapasalo, Bifunctional bioceramics stimulating osteogenic differentiation of a gingival fibroblast 
							and inhibiting plaque biofilm formation, Biomaterials Science 4(4) (2016) 639-
							651.##[61] S. Hu, C. Ning, Y. Zhou, L. Chen, K. Lin, J. Chang, Antibacterial activity of 
							silicate bioceramics, Journal of Wuhan University of Technology-Mater. Sci. Ed. 
							26(2) (2011) 226-230.##[62] R. Keihan, E. Salahinejad, Inorganic-salt coprecipitation synthesis, fluoride-doping, bioactivity and physiological pH buffering evaluations of bredigite, 
							Ceramics International 46(9) (2020) 13292-13296.##[63] M. Kouhi, M. Shamanian, M. Fathi, A. Samadikuchaksaraei, A. Mehdipour, 
							Synthesis, Characterization, In Vitro Bioactivity and Biocompatibility Evaluation 
							of Hydroxyapatite/Bredigite (Ca7 MgSi4 O16) Composite Nanoparticles, JOM 68(4) 
							(2016) 1061-1070.##[64] S.N. Dezfuli, S. Leeflang, Z. Huan, J. Chang, J. Zhou, Fabrication of novel 
							magnesium-matrix composites and their mechanical properties prior to and during 
							in vitro degradation, Journal of the Mechanical Behavior of Biomedical Materials 
							67 (2017) 74-86.##[65] Q. Fu, E. Saiz, M.N. Rahaman, A.P. Tomsia, Bioactive glass scaffolds for bone 
							tissue engineering: state of the art and future perspectives, Materials Science and 
							Engineering: C 31(7) (2011) 1245-1256.##[66] H. Ghomi, R. Emadi, Fabrication of bioactive porous bredigite (Ca7
							MgSi4 O16) scaffold via space holder method, International Journal of Materials Research 
							109(3) (2018) 257-264.##[67] A. Mansourighasri, N. Muhamad, A.B. Sulong, Processing titanium foams 
							using tapioca starch as a space holder, Journal of Materials Processing Technology 
							212(1) (2012) 83-89. ##[68] M. Kouhi, M. Fathi, V. Jayarama Reddy, S. Ramakrishna, Bredigite Reinforced Electrospun Nanofibers for Bone Tissue Engineering, Materials Today: 
							Proceedings 7 (2019) 449-454.##[69] M. Kouhi, M. Fathi, M.P. Prabhakaran, M. Shamanian, S. Ramakrishna, Poly 
							L lysine-modified PHBV based nanofibrous scaffolds for bone cell mineralization 
							and osteogenic differentiation, Applied Surface Science 457 (2018) 616-625.##[70] A. Khademhosseini, R. Langer, A decade of progress in tissue engineering, 
							Nature Protocols 11(10) (2016) 1775-1781.##[71] B. Baumann, T. Jungst, S. Stichler, S. Feineis, O. Wiltschka, M. Kuhlmann, 
							M. Lindén, J. Groll, Control of Nanoparticle Release Kinetics from 3D Printed 
							Hydrogel Scaffolds, Angewandte Chemie International Edition 56(16) (2017) 
							4623-4628.##[72] Y. Zhang, D. Zhai, M. Xu, Q. Yao, H. Zhu, J. Chang, C. Wu, 3D-printed 
							bioceramic scaffolds with antibacterial and osteogenic activity, Biofabrication 9(2) 
							(2017) 025037.##[73] I. Sabree, J.E. Gough, B. Derby, Mechanical properties of porous ceramic 
							scaffolds: Influence of internal dimensions, Ceramics International 41(7) (2015) 
							8425-8432.##[74] R. Wang, P. Zhu, W. Yang, S. Gao, B. Li, Q. Li, Direct-writing of 3D periodic 
							TiO2 bio-ceramic scaffolds with a sol-gel ink for in vitro cell growth, Materials  
							Design 144 (2018) 304-309.##[75] C. Qin, D. Che, D. Liu, Z. Zhang, Y. Feng, Preparation and characterization 
							of different micro/nano structures on the surface of bredigite scaffolds, Scientific 
							Reports 13(1) (2023) 9072.##[76] D. Liu, X. Zhou, F. Wang, Y. Feng, Y. Shi, Research and analysis of the properties of bredigite-based 3D-printed bone scaffolds, IJB 9(3) (2023). 
							##[77] Y. Xuan, L. Li, C. Zhang, M. Zhang, J. Cao, Z. Zhang, The 3D-Printed Ordered Bredigite Scaffold Promotes Pro-Healing of Critical-Sized Bone Defects 
							by Regulating Macrophage Polarization, International Journal of Nanomedicine 
							18(null) (2023) 917-932.##[78] S.L. Sing, W.Y. Yeong, F.E. Wiria, B.Y. Tay, Z. Zhao, L. Zhao, Z. Tian, S.Yang, Direct selective laser sintering and melting of ceramics: a review, Rapid 
							Prototyping Journal 23(3) (2017) 611-623.##[79] S.L. Sing, F.E. Wiria, W.Y. Yeong, Selective laser melting of lattice structures: 
							A statistical approach to manufacturability and mechanical behavior, Robotics and 
							Computer-Integrated Manufacturing 49 (2018) 170-180.##[80] Q. Shi, D. Gu, M. Xia, S. Cao, T. Rong, Effects of laser processing parameters 
							on thermal behavior and melting/solidification mechanism during selective laser 
							melting of TiC/Inconel 718 composites, Optics  Laser Technology 84 (2016) 
							9-22.##[81] Y. Yang, F. Yuan, C. Gao, P. Feng, L. Xue, S. He, C. Shuai, A combined strategy to enhance the properties of Zn by laser rapid solidification and laser alloying, 
							Journal of the Mechanical Behavior of Biomedical Materials 82 (2018) 51-60.##[82] Y. Zhang, L. Wu, X. Guo, S. Kane, Y. Deng, Y.-G. Jung, J.-H. Lee, J. Zhang, 
							Additive Manufacturing of Metallic Materials: A Review, Journal of Materials Engineering and Performance 27(1) (2018) 1-13.
							##[83] C. Gao, M. Yao, C. Shuai, S. Peng, Y. Deng, Nano-SiC reinforced Zn biocomposites prepared via laser melting: Microstructure, mechanical properties and 
							biodegradability, Journal of Materials Science Technology 35(11) (2019) 2608-
							2617.##[84] C. Shuai, Y. Li, Y. Yang, S. Peng, W. Yang, F. Qi, S. Xiong, H. Liang, L. Shen, 
							Bioceramic enhances the degradation and bioactivity of iron bone implant, Materials Research Express 6(11) (2019) 115401.
							##[85] A.R. Boccaccini, S. Keim, R. Ma, Y. Li, I. Zhitomirsky, Electrophoretic deposition of biomaterials, Journal of The Royal Society Interface 7(suppl_5) (2010) 
							S581-S613.##[86] I. Corni, M.P. Ryan, A.R. Boccaccini, Electrophoretic deposition: From traditional ceramics to nanotechnology, Journal of the European Ceramic Society 28(7) 
							(2008) 1353-1367.##[87] C.T. Kwok, P.K. Wong, F.T. Cheng, H.C. Man, Characterization and corrosion behavior of hydroxyapatite coatings on Ti6Al4V fabricated by electrophoretic 
							deposition, Applied Surface Science 255(13) (2009) 6736-6744.##[88] Q. Chen, L. Cordero-Arias, J.A. Roether, S. Cabanas-Polo, S. Virtanen, A.R. 
							Boccaccini, Alginate/Bioglass® composite coatings on stainless steel deposited 
							by direct current and alternating current electrophoretic deposition, Surface and 
							Coatings Technology 233 (2013) 49-56.##[89] M. Razavi, M. Fathi, O. Savabi, L. Tayebi, D. Vashaee, Biodegradable Magnesium Bone Implants Coated with a Novel Bioceramic Nanocomposite, Materials 
							13(6) (2020) 1315.##[90] W.C. Oliver, G.M. Pharr, Measurement of hardness and elastic modulus by 
							instrumented indentation: Advances in understanding and refinements to methodology, Journal of Materials Research 19(1) (2004) 3-20.
							##[91] F.A.b.A. Azam, R. Shamsudin, Preliminary study of raw material for calcium silicate/PVA coating on Ti-6Al-4V alloy, AIP Conference Proceedings 1678(1) 
							(2015).##[92] N. Iqbal, R. Nazir, A. Asif, A.A. Chaudhry, M. Akram, G.Y. Fan, A. Akram, R. 
							Amin, S.H. Park, R. Hussain, Electrophoretic deposition of PVA coated hydroxyapatite on 316L stainless steel, Current Applied Physics 12(3) (2012) 755-759.
							##[93] H. Pingan, J. Mengjun, Z. Yanyan, H. Ling, A silica/PVA adhesive hybrid 
							material with high transparency, thermostability and mechanical strength, RSC 
							Advances 7(5) (2017) 2450-2459.##[94] A. Timofejeva, M. D’Este, D. Loca, Calcium phosphate/polyvinyl alcohol 
							composite hydrogels: A review on the freeze-thawing synthesis approach and applications in regenerative medicine, European Polymer Journal 95 (2017) 547-565.
							##[95] C. Gao, M. Yao, S. Li, P. Feng, S. Peng, C. Shuai, Highly biodegradable and 
							bioactive Fe-Pd-bredigite biocomposites prepared by selective laser melting, Journal of Advanced Research 20 (2019) 91-104.
							##[96] M. Razavi, M. Fathi, O. Savabi, L. Tayebi, D. Vashaee, Improvement of in vitro behavior of an Mg alloy using a nanostructured composite bioceramic coating, 
							Journal of Materials Science: Materials in Medicine 29(10) (2018) 159.
							##[97] C. Deng, R. Lin, M. Zhang, C. Qin, Q. Yao, L. Wang, J. Chang, C. Wu, Micro/
							Nanometer-Structured Scaffolds for Regeneration of Both Cartilage and Subchondral Bone, Advanced Functional Materials 29(4) (2019) 1806068.
							##[98] A. Khandan, N. Ozada, S. Saber-Samandari, M. Ghadiri Nejad, On the mechanical and biological properties of bredigite-magnetite (Ca7
							MgSi4 O16-Fe3 O4) nanocomposite scaffolds, Ceramics International 44(3) (2018) 3141-3148.
							##[99] E. Askari, M. Rasouli, S.F. Darghiasi, S.M. Naghib, Y. Zare, K.Y. Rhee, Reduced graphene oxide-grafted bovine serum albumin/bredigite nanocomposites 
							with high mechanical properties and excellent osteogenic bioactivity for bone tissue engineering, Bio-Design and Manufacturing 4(2) (2021) 243-257.
							##[100] M. Kouhi, M.P. Prabhakaran, M. Shamanian, M. Fathi, M. Morshed, S. Ramakrishna, Electrospun PHBV nanofibers containing HA and bredigite nanoparticles: Fabrication, characterization and evaluation of mechanical properties and 
							bioactivity, Composites Science and Technology 121 (2015) 115-122.
							##[101] M. Kouhi, M. Fathi, M.P. Prabhakaran, M. Shamanian, S. Ramakrishna, 
							Enhanced proliferation and mineralization of human fetal osteoblast cells on 
							PHBV-bredigite nanofibrous scaffolds, Materials Today: Proceedings 5(7, Part 3) 
							(2018) 15702-15709. ##[102] M. Kouhi, V. Jayarama Reddy, S. Ramakrishna, GPTMS-Modified Bredigite/PHBV Nanofibrous Bone Scaffolds with Enhanced Mechanical and Biological 
							Properties, Applied Biochemistry and Biotechnology 188(2) (2019) 357-368.
							##[103] M. Razavi, M. Fathi, O. Savabi, D. Vashaee, L. Tayebi, Improvement of Biodegradability, Bioactivity, Mechanical Integrity and Cytocompatibility Behavior 
							of Biodegradable Mg Based Orthopedic Implants Using Nanostructured Bredigite 
							(Ca7 MgSi4 O16) Bioceramic Coated via ASD/EPD Technique, Annals of Biomedical Engineering 42(12) (2014) 2537-2550.
							##[104] M. Razavi, M. Fathi, O. Savabi, D. Vashaee, L. Tayebi, Regenerative influence of nanostructured bredigite (Ca7
							MgSi4O16)/anodic spark coating on biodegradable AZ91 magnesium alloy implants for bone healing, Materials Letters 155 
							(2015) 97-101.##[105] A. Nadi, M. Khodaei, M. Javdani, S.A. Mirzaei, M. Soleimannejad, L. 
							Tayebi, S. Asadpour, Fabrication of functional and nano-biocomposite scaffolds 
							using strontium-doped bredigite nanoparticles/polycaprolactone/poly lactic acid 
							via 3D printing for bone regeneration, International Journal of Biological Macromolecules 219 (2022) 1319-1336.
							##[106] M. Eilbagi, R. Emadi, K. Raeissi, M. Kharaziha, A. Valiani, Mechanical 
							and cytotoxicity evaluation of nanostructured hydroxyapatite-bredigite scaffolds 
							for bone regeneration, Materials Science and Engineering: C 68 (2016) 603-612.
							##[107] A. Jadidi, E. Salahinejad, Mechanical strength and biocompatibility of bredigite (Ca7
							MgSi4O16) tissue-engineering scaffolds modified by aliphatic polyester 
							coatings, Ceramics International 46(10, Part B) (2020) 16439-16446 </REF>
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