Electrochemical sensing of Nalbuphine in pharmaceutical samples using amplified MgO/CNTs nanocomposite electrode en en MgO/CNTs nanocomposite was synthesized by a simple strategy and used for modification of paste electrode. The paraffin oil (PI) and 1-Butyl-3-methylimidazolium methyl sulfate (BMMS) were used as binders for fabrication of MgO/CNTs/PI/BMMS/PE. The MgO/CNTs/PI/BMMS/PE introduce as new analytical sensor for determination of nalbuphine in the concentration range 1.0 nM – 400 µM. In final step, the MgO/CNTs/PI/BMMS/PE was used for monitoring of nalbuphine in injection and serum samples with acceptable recovery data 1 3 Samad Jafari Zare Department of Chemical Engineering Ayatollah Amoli Branch, Islamic Azad University Iran info@jourcc.com Mojtaba Masomi Department of Chemical Engineering Ayatollah Amoli Branch, Islamic Azad University Iran mojtabamasomi@yahoo.com Mazyar Sharifzadeh Baei Department of Chemical Engineering Ayatollah Amoli Branch, Islamic Azad University Iran info@jourcc.com Shahram Naghizadeh Raeisi Department of Food Science and Technology Ayatollah Amoli Branch, Islamic Azad University Iran info@jourcc.com Seyed-Ahmad Shahidi Department of Food Science and Technology Ayatollah Amoli Branch, Islamic Azad University Iran info@jourcc.com Nalbuphine MgO/CNTs nanocomposite Ionic liquid Drug monitoring Article1.pdf [1] B. Vissers, H. Bohets, J. Everaert, P. Cool, E. Vansant, F. Du Prez, J. Kauffmann, L.J. 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