1 A review of clinical applications of graphene quantum dot-based composites https://jourcc.com/index.php/jourcc/article/view/jcc116 10.29252/jcc.1.1.6 20.1001.1.26765837.2019.1.1.6.5 1 This review represent an overview of the graphene quantum dots synthesis and their application as carriers or probes for sensor, imaging, drug delivery and diagnosing of diseases. More specifically, recent advances in the integration of QDs with drug formulations for therapy and their potential toxicity in vitro and in vivo are highlighted. The current findings and challenges for optimizing QD/drug formulations with respect to optimal size and stability, short-term and long-term toxicity, and in vivo applications are described. 31 40 Ebadollah Asadi Amirkabir University of Technology Iran info@jourcc.com Arash Fassadi Chimeh Science and Research Branch, Islamic Azad University Iran info@jourcc.com Sahar Hosseini Rajiv Gandhi University India info@jourcc.com Seyedhamidreza Rahimi Islamic Azad University, Tehran Science Research Branch Iran info@jourcc.com Bijan Sarkhosh University of Isfahan Iran info@jourcc.com Leila Bazli Iran University of Science and Technology Iran leilabazli64@gmail.com Rozhin Bashiri Pharmaceutical Science branch, Islamic Azad University Iran info@jourcc.com Amir Hossein Vakili Tahmorsati Islamic Azad University, Central Tehran Branch Iran info@jourcc.com Quantum dots Graphene Cancer Drug Delivery Diagnosis Article6.pdf [1] C. Yu, X. Li, F. Zeng, F. Zheng, S. 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